Research Update – Moringa shows potential to relieve pain and inflammation

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The following research abstract is a copy from Pubmed. The anti-inflammatory characteristics of Moringa have long been listed as one of its many benefits.  The following abstract documents that finding.

Title:

Purification of a Chitin-Binding Protein from Moringa oleifera Seeds with Potential to Relieve Pain and Inflammation.

Authors:

Pereira ML, de Oliveira HD, de Oliveira JT, Gifoni JM, de Oliveira Rocha R, de Oliveira Bezerra de Sousa D, Vasconcelos IM.

Source:

Universidade Federal do Ceará, Departamento de Bioquímica e Biologia Molecular, 60440-990, Fortaleza, CE, Brazil. imvasco@ufc.br.

Abstract:

Moringa oleifera Lam. is a perennial multipurpose tree that has been successfully used in folk medicine to cure several inflammatory processes. The aim of this study was to purify and characterize a chitin-binding protein from Moringa oleifera seeds, named Mo-CBP(4), and evaluate its antinociceptive and anti-inflammatory effects in vivo. The protein was purified by affinity chromatography on chitin followed by ion exchange chromatography. Acetic acid-induced abdominal constrictions assay was used for the antinociceptive and anti-inflammatory activity assessments. Mo-CBP(4) is a glycoprotein (2.9% neutral carbohydrate) composed of two protein subunits with apparent molecular masses of 28 and 18 kDa (9 kDa in the presence of reducing agent). The intraperitoneal injection of Mo-CBP(4) (3.5 and 10 mg/kg) into mice 60 min before acetic acid administration potently and significantly reduced the occurrence of abdominal writhing in a dose dependent manner by 44.7% and 100%, respectively. In addition, the oral administration of the protein (10 mg/kg) resulted in 18% and 52.8% reductions in abdominal writhing when given 30 and 60 min prior to acetic acid administration, respectively. Mo-CBP(4), when administered by intraperitoneal route, also caused a significant and dose-dependent inhibition of peritoneal capillary permeability induced by acid acetic and significantly inhibited leukocyte accumulation in the peritoneal cavity. In conclusion, this pioneering study describes that the chitin-binding protein Mo-CBP(4), from M. oleifera seeds, exhibits anti-inflammatory and antinociceptive properties and scientifically supports the use of this multipurpose tree in folk medicine.

PMID: 21675945 [PubMed – as supplied by publisher]

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5 Responses to “Research Update – Moringa shows potential to relieve pain and inflammation”

  1. Therre Says:

    It is helpful in strengthening the immune system. To use moringa for HIV and AIDS, one can take moringa powder, moringa capsule or use the moringa leaves in food preparations.

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    other ailments that be cured with moringa oliveira plant.

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